Quality care, close to home.

About Signature

We are the largest physician-owned multi-specialty medical group serving patients in the St. Louis and Kansas City regions.
We are committed to keeping healthcare decisions where they belong - in the hands of physicians and their patients.

Our Response to COVID-19

The practices of Signature Medical Group are closely monitoring the ever-changing COVID-19 event. We are actively taking all necessary measures to protect our patients and staff from the spread of the novel coronavirus (COVID-19). Please visit our Coronavirus Resource pages to get up to date information about our efforts. 

  • 500K Patient Visits
    Every Year
  • 150+ Physicians &
    Advanced Clinicians
  • 45+ St. Louis & Kansas City
    Area Locations
  • 22+ Specialties &

Signature Orthopedics logo

All five St. Louis area Signature orthopedic divisions (Mid County Orthopaedic Surgery & Sports Medicine, Premier Care Orthopedics & Sports Medicine, St. Charles Orthopaedic Surgery Associates, Jefferson County Orthopaedic Surgery & Sports Medicine, and Tesson Ferry Spine & Orthopedic Center) have come together under a single, recognizable name – Signature Orthopedics.