Signature Medical Group - Quality Care, Close to Home

We are the largest physician-owned multi-specialty medical group serving patients in both the St. Louis and Kansas City regions. We are committed to keeping health care decisions where they belong in the hands of physicians and their patients.

Each day we provide you, our patients, with choices for accessible, affordable and quality health care.


Our Response to COVID-19

The practices of Signature Medical Group are closely monitoring the ever-changing novel COVID-19 event. We are actively taking all necessary measures to protect our patients and staff from the spread of the coronavirus (COVID-19). Please visit our Coronavirus Resource Page to get up-to-date information about our efforts.

  • 500K Patient Visits
    Every Year
  • 130+ Physicians &
    Advanced Clinicians
  • 35+ St. Louis & Kansas City
    Area Locations
  • 22+ Specialties &
    Subspecialties