Coles E. L'Hommedieu, MD

Coles E. L'Hommedieu

Contact Information

  • Office 314-849-0311
  • Fax 314-849-4423
  • After Hours 314-470-8735


Main Location

Signature Orthopedics South County
12639 Old Tesson Road
Suites 100 and 115
St. Louis, MO 63128
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Hospital Affiliations

Old Tesson Surgery Center
St. Luke's Des Peres Hospital
SSM Health St. Clare Hospital - Fenton
Mercy Hospital South

Areas of Interest

Total Joint Replacements, Trauma


Dr. Coles L'Hommedieu is a board-certified orthopedic surgeon. He specializes in and treats a variety of orthopedic conditions, including total joint replacements and trauma. His practice focuses on hip and knee replacement surgery.

Dr. L'Hommedieu serves as the President of the Board at Signature Medical Group, and is also co-founder of CL Medical Technologies. Has consulted for implant design and process development for Lima, United Orthopedics, DePuy, and Zimmer-Biomet.

Outside of work, Dr. L'Hommedieu is in a band, enjoys playing soccer, and has participated in several medical mission trips to Belize.

Dr. L'Hommedieu accepts all major insurances. For more information, please visit our Insurance page.

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Residency: Saint Louis University Hospital
Internship: Saint Louis University Hospital
Medical School: Southern Illinois University School of Medicine

Certifications & Organizations

American Board of Othopaedic Surgery

"Very friendly staff. Very kind and helpful as this was my first visit. Dr. L’Hommedieu was wonderful! He really took time to listen to me and answered all my questions. He was the only doctor to ever recommend physical therapy to me. It gave me hope that I could avoid surgery. I highly recommend them!"

Patient of Dr. L'Hommedieu