We are your St. Louis pain relief specialist

Better Doctors Better Care

Knee pain can get in the way of almost every aspect of your life.

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Why Choose Us

Board-Certified

Signature Orthopedics physicians are independent practitioners and experts in orthopedic care.

Personalized Care

We believe in patient-centered care. Our priority is to work in with you to determine the best treatment.

Options

Our physicians will discuss non-invasive and alternative options in addition to traditional treatments.

Convenient

With over 10 convenient locations we offer accessible and affordable health care close to home. Telehealth appointments too!

Why Choose Us

We Will Help You Find Relief From Knee Pain

Knee pain can get in the way of almost every aspect of your daily life. Often times, the key to getting better is good advice and the right diagnosis. If knee pain is limiting your movement, the experienced orthopedic specialists at Signature Orthopedics can help you achieve optimal health and wellness. Our board-certified, fellowship-trained orthopedic surgeons are recognized leaders in providing innovative treatments – both surgical and conservative – for a wide range of knee conditions.

Saint Louis Knee Doctors

At Signature Orthopedics, we emphasize patient education — because knowing matters. Maybe your knee pain struck suddenly after an injury on a playing field, or perhaps it developed gradually through ongoing wear and tear. Either way, we will pinpoint the problem so we can get you on the path to recovery as quickly as possible. Whether the source of your discomfort turns out to be arthritis, bursitis, a torn ligament, or a sprain, strain, or fracture, we'll utilize the latest research and technology to get you the answers you need, then work closely with you to develop a personalized treatment plan to help you manage your knee pain.

Think you need a knee replacement?

Quite often patients hold off seeing a doctor because they think the only solution is a total knee replacement. Things have changed. There are many options available to alleviate knee pain, not just surgery.

Safety First

During the COVID-19 crisis, doctors’ offices and healthcare facilities are considered essential services. Therefore, Signature Orthopedics continues to treat patients while taking extra precautions to maintain the safety and well-being of the patients in our care.

Signature Orthopedics continues to be a “one-stop shop,” providing onsite imaging (X-ray and MRI), casting, splinting, injections, and other immediate orthopedic care services.

Don't live with knee pain any longer

The ability to move freely and without pain is essential to living your life to the fullest. Contact Signature Orthopedics to request an appointment today, and take your first step toward overcoming your knee pain.

Common Injuries & Issues We Treat Include:

  • Sports Injuries
  • ACL Injuries
  • Combined Knee Ligament Injuries
  • Dislocations
  • Swollen Knees
  • Knee Bursitis
  • Ongoing Knee Pain
  • Arthritis
  • Trips & Falls
  • Meniscal Tears
  • Overuse Injuries
  • Runner's Knee
  • Sprains, Strains & Fractures

Doctors

Brian A. FisselMD

Brian A. Fissel

St. Louis, MO

12639 Old Tesson Road
Suite 100 & Suite 115
St. Louis, MO 63128

Kevin J. QuigleyMD

Kevin J. Quigley

O'Fallon, MO

9323 Phoenix Village Parkway
Winghaven
O'Fallon, MO 63368

Matthew P. MelanderDO

Matthew P. Melander

O'Fallon, MO

9323 Phoenix Village Parkway
Winghaven
O'Fallon, MO 63368

Robert G. MedlerMD

Robert G. Medler

St. Louis, MO

12639 Old Tesson Road
Suite 100 & Suite 115
St. Louis, MO 63128

John B. PowellMD

John B. Powell

O'Fallon, MO

9323 Phoenix Village Parkway
Winghaven
O'Fallon, MO 63368

Craig R. RubleMD

Craig R. Ruble

Festus, MO

1390 Highway 61
Suite G1000
Festus, MO 63028

Christopher W. PalmerDO

Christopher W. Palmer

St. Louis, MO

12639 Old Tesson Road
Suite 100 & Suite 115
St. Louis, MO 63128

Coles E. L'HommedieuMD

Coles E. L'Hommedieu

St. Louis, MO

12639 Old Tesson Road
Suite 100 & Suite 115
St. Louis, MO 63128

Vince J. LaiMD

Vince J. Lai

St. Louis, MO

845 North New Ballas Court
Suite 200
St. Louis, MO 63141

Anthony J. BerniMD

Anthony J. Berni

O'Fallon, MO

9323 Phoenix Village Parkway
Winghaven
O'Fallon, MO 63368

James E. SchabergMD

James E. Schaberg

O'Fallon, MO

9323 Phoenix Village Parkway
Winghaven
O'Fallon, MO 63368

Robert H. SigmundMD

Robert H. Sigmund

St. Louis, MO

12639 Old Tesson Road
Suite 100 & Suite 115
St. Louis, MO 63128

Ashley H. AliMD

Ashley H. Ali

St. Louis, MO

12639 Old Tesson Road
Suite 100 & Suite 115
St. Louis, MO 63128
  • 170k Patient Visits
    Every Year
  • 40 Orthopedic Physicians &
    Advanced Clinicians
  • 9 St. Louis Area
    Locations
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