John B. Powell, MD

John B. Powell

Contact Information

  • Office 636-561-0871
  • After Hours 636-561-0871
  • Fax 636-561-5031


Main Location

Signature Orthopedics - O'Fallon
9323 Phoenix Village Parkway
O'Fallon, MO 63368
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Other Locations

Signature Orthopedics - St. Charles
5301 Veterans Memorial Parkway
St. Peters, MO 63376

Hospital Affiliations

Barnes-Jewish St. Peters Hospital
Mid Rivers Surgery Centers
Progress West Hospital
SSM Health St. Joseph Hospital - St. Charles
SSM Health St. Joseph Hospital - Lake Saint Louis
Total Joint Center of St. Louis

Areas of Interest

Knee Conditions, Hip Conditions, Shoulder Conditions, Total Joint/Compartmental, Arthritis, Reconstructive Surgery, Arthroscopic Surgery


Dr. Powell is a board-certified orthopedic surgeon. He specializes in knee, hip and shoulders conditions, offering both non-operative and operative treatment options. Every year, Dr. Powell participates in a mission trip to the Dominican Republic to perform hip and knee replacements.

Outside of work, Dr. Powell enjoys spending time with his children, golfing, and biking.

Dr. Powell accepts all major insurances. For more information go to our Insurance page.

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Residency: Saint Louis University Hospitals
Medical School: University of Missouri School of Medicine

Certifications & Organizations

American Board of Orthopaedic Surgery

"I became an orthopedic surgeon because it is very rewarding to help a person maintain or regain his or her activity level. Fixing a fracture, replacing an arthritic joint, or reconstructing a torn ligament are examples of procedures I perform that help people stay active."

John B. Powell, MD